201*Ⱥڌ(sh)(yn)վйY(ji)
ڌ(sh)(yn)վ201*ȿйY(ji)
201*Ǻڌ(sh)(yn)վĿйȡÿԽʽl(f)չһꡣ@һ(xing)ĿՓĶȡһijɿmȻ@ЩɿǺܴnjںڌ(sh)(yn)վǾͻ
ڌ(sh)(yn)վԺI(lng)(do)P(gun)c֧^ȥһĹ(dng)Уڌ(sh)(yn)վI(lng)(do)MıMڌ(sh)(yn)վI(y)l(f)չڵĺˮվI(lng)(do)I(lng)ڌ(sh)(yn)վȫwT˷kh(hun)ɵIJڿ(xing)Ŀ(bo)(xing)Ŀ(zh)еȷSȡ^гЧĘI(y)挦P(gun)rM(jn)пY(ji)
һ201*(xing)Ŀ@͈(zh)r
ڌ(sh)(yn)վ201*@ÿ(bo)@(xing)Ŀ6(xing)
Ѓ(xing)뼉ԿԺИI(y)(w)M(fi)(xing)քe飺1Q㽶a(chn)P(gun)Ig(sh)о(xing)ĿԴ_Ժ(xing)Ŀ(xing)Ŀ(jng)M(fi)30fԪ2Q߾c㽶ϵķәC(j)(xing)ĿԴh(hun)cֲﱣo(h)о_Ժ(xing)Ŀ(xing)Ŀ(jng)M(fi)20fԪ
ʡȻƌW(xu)(xing)Qքe飺ʡ㽶{(dio)鼰ԭϵb㽶ѪӵķxͽY(ji)(gu)bоGFPʾۙо㽶߾Ⱦ㽶ϵ^
ʡc(din)Ƽ(xing)Ŀ1(xing)㽶ˮһwЧ༼g(sh)ԇ(yn)оcʾ(xing)Ŀ(zh)r(xing)ĿӋ(j)Ҫքeژ|~ȵز㽶w(x)sо㽶ˮʸЧüg(sh)о㽶{(dio)鼰l(f)Ҏ(gu)оÃ(ni)(x)㽶ήо㽶o~ЙC(j)ʵƼ䑪(yng)о㽶ӹP(gun)Ig(sh)оȵP(gun)(sh)(yn)Ŀǰ(sh)(yn)M(jn)С(xing)ĿҲM(jn)Ю(dng)ȡһĽY(ji)
201*(xing)Ŀ@r
201*Ⱥڌ(sh)(yn)վ(bo)(xing)Ŀ@5(xing)ĿЇҡ948(xing)Ŀ2(xing)Ŀρ(xing)1(xing)ρИI(y)(w)M(fi)(xing)2(xing)н(jng)M(fi)_(d)200fԪ@Щ(xing)Ŀī@麣ڌ(sh)(yn)վ_չĿй춨ˈ(jin)(sh)ĻA(ch)w飺
һҡ948(xing)Ŀ2(xing)
1(xing)ĿQ㽶wS坍ÓzˇƷP(gun)Ig(sh)M(jn)MM(jn)㽶wSøÓzg(sh)ϵӡȿƌW(xu)cI(y)оίT\g(sh)ParukuttyammaPremaСParukuttyammaPremaҪоI(lng)?yn)ﻯW(xu)Ͱl(f)
2(xing)ĿQ㽶NP(gun)Ig(sh)M(jn)(xing)Ŀ(ni)ݣM(jn)g(sh)ɷ棺
1㽶Ng(sh)㽶Ҹ(x)B(yng)g(sh)ֲwȡIJλͬAεB(yng)䷽B(yng)r(sh)gwߵT(do)ȣ㽶ԭ|(zh)wB(yng)g(sh)(ϵĻȡIJλøƄxPHֵBo(h)(x)x(x)ںϵ)zD(zhun)g(sh)ͬD(zhun)wr(nng)UȡȾr(sh)g|(zh)dwĘ(gu)ӵx늓ȣ
2ܻ
Replicase-associatedprotein(Rep)gene(f)øρ(xing)1(xing)
ԓ(xing)Ŀxַںʡ㽶a(chn)^(q)Y(ji)ϱλČ(sh)Hr͇㽶a(chn)I(y)g(sh)wϵھCԇ(yn)վİl(f)չĿ(bio)΄(w)ҪO(sh)㽶(bio)(zhn)ʾ@^(q)ַxIJС(xing)Ŀݘ(bio)(zhn)a(chn)ʾ^(q)150IJ(bio)(zhn)a(chn)ʾ^(q)100ԓʾ^(q)Й(qun)`҆λO(sh)(bio)(zhn)ʾ@250ݘ(bio)(zhn)ʾ@Ҫ㽶CB(yng)o(h)g(sh)(ji)ˮ(ji)ʼg(sh)IJ(bio)(zhn)ʾ@^(q)ҪԹ(ji)ˮ(ji)ʼg(sh)˰bˮһwιʩϵy(tng)cǰڱλоIJ(xing)Ŀƶ(yn)o(h)o(h)r(nng)´ʩA(y)Ӌ(j)(xing)Ŀ(sh)ʩ5gʾ201*ݗƏVe_(d)2fӖ(xn)I(y)g(sh)a(chn)ƏVˆT500˴ͨ^(bio)(zhn)ʾ@O(sh)r(nng)w㽶(bio)(zhn)a(chn)g(sh)Ӯa(chn)߹(sh)Ʒ|(zh)(ji)sɱ߽(jng)(j)ЧČ(sh)Ч߀r(nng)ˆTr(nng)(bio)(zhn)a(chn)RF(xin)㽶a(chn)g(sh)ˮƽ
ρИI(y)(w)M(fi)2(xing)
1(xing)ĿQ㽶Ǵx(sh)Ʒ|(zh)γc{(dio)õо
(xing)Ŀ(ni)ݣͨ^˽㽶(sh)l(f)^й(sh)MǷe|(zh)ɫغ̓(ni)Դص׃Ҏ(gu)̽ӑ㽶(sh)l(f)^Ѓ(ni)ɷּҪxøSC|(zh)V|(zh)Ԫصȵ׃Ҏ(gu)ɺP(gun)ϵͨ^ˮƽо{(dio)㽶Ʒ|(zh)ṩՓ(j)2(xing)ĿQw{(dio){(dio)(ji)㽶ɺƷ|(zh)о
(xing)Ŀ(ni)ݣ(xing)Ŀᘌ㽶п¡ĹȰÓøGlutamatedecarboxylase,GAD,MaGAD1͙ϳøGlyoxysomalcitratesynthaseGCSMaGCSо㽶(sh)^е{(dio)üC(j)Ҫо(ni)Ѓɂ(g)棺1ϩ1-MCPȷʽ̎㽶(sh)оԓڸ̎ı_(d)ʽ2w{(dio)عȰÓø͙ϳøı_(d)оc(sh)Ʒ|(zh)γɵP(gun)ϵͬϩ㽶r·
201*Ƽlƽ_O(sh)r
ڌ(sh)(yn)վ201*ُ(xing)Ŀr
201*(zh)Ѓ(xing)@ĿЗlƽ_O(sh)(xing)Ŀ㽶W(xu)c(din)(sh)(yn)죬IJ㽶a(chn)I(y)g(sh)c(chung)»ػA(ch)O(sh)ʩ@ɂ(g)(xing)ĿM(jn)Ю(dng)УA(y)Ӌ(j)201*깤ƺڌ(sh)(yn)վĿkl
ġƼƏVc(w)r(nng)r
J(rn)䌍(sh)ЇᎧr(nng)I(y)ƌW(xu)ԺƼM(jn)M(jn)впhr(nng)յľͬr(sh)`пƌW(xu)l(f)չ^(w)r(nng)Ŀ(bio)ڌ(sh)(yn)վГ(dn)r(nng)I(y)Ƽ˾P(gun)r(nng)ƏVcwϵO(sh)M(yu)r(nng)a(chn)Ʒشg(sh)ƏVʾhr(nng)ˆTӖ(xn)(xing)Ŀ(xing)Ŀ(sh)ʩMᎧI(lng)Č_չr(nng)I(y)Ƽl(xing)Ӗ(xn)߀c(zi)Ȟ(zi)Y(ji)ϣ_L(fng)Σڱȵķ(w)r(nng)УӖ(xn)r(nng)ˆT201*l(f)ſƼY8000ԣ(w)w14(g)пhm(x)ķ(w)r(nng)(jin)(sh)A(ch)
Ƽ
ںڌ(sh)(yn)վĚvʷԭзĹ]Уȱڿй
Ľ(jng)(yn)Ǻڌ(sh)(yn)վԿƌW(xu)l(f)չ^ָ(do)˼˞鱾đB(ti)ȣJ(rn)W(xu)(x)bȡІλڿйijɹ(jng)(yn)c֮̎ڌ(sh)(yn)վİl(f)չD(zhun)͵춨(sh)ĹA(ch)
201*ڌ(sh)(yn)վɳP(gun)ˆTW(xu)(x)Ӗ(xn)ȣҪ㽶ή²C(j)زԌW(xu)g(sh)ӑ։^(q)y䷽ʩʹӑ(zhn)r(nng)I(y)㽶a(chn)I(y)g(sh)wϵg(sh)Ӗ(xn)㽶a(chn)I(y){(dio)йˮһwg(sh)Ӗ(xn)r(nng)Ar(nng)I(y)Ƽ(bo)Ӗ(xn)ϾӢZӖ(xn)Ϯa(chn)I(y){(dio)е@һꮔ(dng)пƼˆTѰl(f)SCIՓ2ƪĺڿ2ƪ
چ}
1wƆ}
Ŀǰڌ(sh)(yn)վr(nng)I(y)I(y)λcҷǠIԿȣˆTˆT(jng)M(fi)ȷژOƣܝMлӵ_չ
2ȱٿ(xing)Ŀ
?yn)wƵĆ}ȱP(gun)(xing)Ŀ֧ĶȱІӽ(jng)M(fi)oӋ(j)_չP(gun)Ŀлӡ
3(sh)(yn)лؽO(sh)
ՈĿk(sh)(yn)ҸؽO(sh)P(gun)(jng)M(fi)߀δλӰ˿лA(ch)lO(sh)M(jn)
4(du)
ںڌ(sh)(yn)վl(f)չĚvʷԭ˲(du)鷽Omˆλl(f)չҪM(jn)P(gun)˲ţenjW(xu)Ǝ^˵M(jn)
ߡ201*깤Ӌ(j)
@O(sh)һоİl(f)չĿ(bio)㽶a(chn)I(y)l(f)չӏ(qing)վƼA(ch)O(sh)ʩ̓xb佨O(sh)eOc(xing)Ŀ(bo)ȡԿ(xing)Ŀӆλl(f)չԆλl(f)չ(do)㽶a(chn)I(y)(gu)ϿƼl(f)չҎ(gu)ɵĿЄ(chung)wϵ͌(sh)(yn)wϵI(lng)֧κͷ(w)㽶a(chn)I(y)A(ch)о¼g(sh)оͮa(chn)Ʒаl(f)ȫߺڌ(sh)(yn)վ(chung)㽶a(chn)I(y)ṩԭʼ(chung)¼g(sh)ƽ_ṩشg(sh)аl(f)ƽ_ṩƼɹD(zhun)ƽ_ṩ⽻M(jn)ل(chung)¼g(sh)ƽ_M(jn)҇㽶a(chn)I(y)
(j)wl(f)չĿ(bio)201*깤Ӌ(j)1лA(ch)lO(sh)
c(din)ץ㽶W(xu)c(din)(sh)(yn)ҺͣIJ㽶a(chn)I(y)g(sh)c(chung)»ػA(ch)O(sh)ʩ(xing)ĿĽO(sh)ƣӴxO(sh)估P(gun)O(sh)ʩͶһڌ(sh)(yn)վİl(f)չD(zhun)䁉|
2(xing)Ŀ(bo)
ڌ(sh)(yn)վŬ˷ڙC(j)ԭÿ(xing)Ŀ(bo)乤eOȡĿ(xing)Ŀ֧֣eOcȻƌW(xu)ρ(xing)ʡԺ𡢻I(y)(w)M(fi)(xing)Ŀ(bo)(j)㽶a(chn)I(y)еĆ}͆λr҂Ŭ¹
1J(rn)҇㽶a(chn)I(y)F(xin)cl(f)չڅݵо(bo)ᘌ㽶a(chn)I(y)ĿǰڵһЩcP(gun)}TṩO(sh)Ҋca(chn)I(y)P(gun)І}҂һĿṩز
2M(jn)аŽٷN|(zh)YԴռͱ棬ȫ㽶N|(zh)YԴN|(zh)YԴM(jn)ur(ji)c(chung)
3ӏ(qing)cλҵĽceOM(jn)cƏV㽶ӹȵM(jn)g(sh)Ӌ(j)201*cӡȇ㽶оӡDorven˾mRDW(xu)оϓ롢INIBAPȇM(jn)㽶YԴϢϵy(tng)ήa(chn)Ʒ_l(f)á㽶cԭӻо㽶Nֲg(sh)Ӗ(xn)㽶YԴھȷČW(xu)(x)c
4ӏ(qing)㽶Ʒ|(zh)о҇㽶a(chn)I(y)l(f)չṩՓ(j)5ӏ(qing)㽶о(bo)eᘌ㽶ή(bo)6M(jn)ȫ(ni)㽶ƷNͼg(sh)ƏVcӖ(xn)3ӏ(qing)(du)齨O(sh)eOM(jn)˲
(du)ĺl(f)չǿІλl(f)չĺģǺڌ(sh)(yn)վĿǰ(du)ڌW(xu)Ǝ^˘Oδڌ(sh)(yn)վĿI(y)l(f)չҪߌӴεĿ˲҂Ӌ(j)201*M(jn)9TʿW(xu)λϵP(gun)ˆTM(jn)
4ӏ(qing)(xing)Ŀ
ҪǼӏ(qing)ճԃ(w)ӏ(qing)(xing)(xing)Ŀڙzȹмӏ(qing)ˆT֮gW(xu)g(sh)(xing)ĿоӋ(j)M(jn)ȵȅR(bo)ӏ(qing)W(xu)g(sh)ʹƶȻ
ڌ(sh)(yn)վk
201*.
U(ku)չx201*c(din)(sh)(yn)ҹY(ji)(bo)V
3
((sh)(yn)Q)c(din)(sh)(yn)
201*ȹY(ji)
(sh)(yn)QІλw£
(sh)(yn)Σˣڣ
201*c(din)(sh)(yn)ҹY(ji)(bo)V
һ(sh)(yn)һr
(sh)(yn)ҵĶλоһ팍(sh)(yn)ҽO(sh)M(jn)չ
r(sh)(yn)ҶλҪоcĿ(bio)(sh)(yn)ҵĵλԼڿƼl(f)չõȣаl(f)Ӻͳɹr
1Г(dn)΄(w)śrГ(dn)΄(w)(sh)(jng)M(fi)(sh)Ҽ
ʡм(xing)Ŀr(xing)ĿM(jn)չrȡ2оɹśr
3Կгɹ飨^5(xing)
ԿгɹɰA(ch)о(yng)ûA(ch)оͻA(ch)ԹҪܴ팍(sh)(yn)ҵĿЌ(sh)͌W(xu)g(sh)ˮƽ䌦(jng)(j)Ƽl(f)չҪؕI(xin)ϵйa(chn)شоɹ
ՈҪBԿгɹҪ(ni)ݡҪĿƼ(chung)ؕI(xin)(ni)Ӱ푵ҪC(j)
Ոÿ(xing)Գɹĺ鼰P(gun)ɹď(f)ӡɹˮƽӰ푵CϵbӆɃ鸽һύ(du)齨O(sh)c˲B(yng)
1(du)Y(ji)(gu)cF(tun)(du)O(sh)ՈҪB(sh)(yn)(du)齨O(sh)
B(yng)reLjF(tun)(du)MۡB(yng)(ni)⃞(yu)˲ŵĴʩȡõijɿ
2(sh)(yn)κ͌W(xu)g(sh)^˼(yu)Ǹɺ飺ՈκҪB(sh)(yn)W(xu)g(sh)^˺̓(yu)Ǹɵr
(yu)Ǹɣ45qָ(sh)(yn)ҽMԁ̶
ˆTЫ@ÇȻƌW(xu)ҿƼM(jn)͇Ҽg(sh)l(f)ȪϿгɹҪߣǰ5@ÇҽܳƌW(xu)863973ϯƌW(xu)ʡƌW(xu)g(sh)صȪһȪϿгɹҪߣǰ5ʡ(chung)F(tun)(du)ˆT(chung)˲ū@ߡ_Žc\(yn)й1⽻cr
2ƽ_rՈҪB̓xO(sh)ʹʣ_
ź̶_l(f)O(sh)fO(sh)ȷr
3\(yn)йrՈҪB(sh)(yn)҃(ni)Ҏ(gu)ƶȽO(sh)
ճW(xu)g(sh)ίT(sh)(yn)ҿзՇ͌W(xu)g(sh)L(fng)⡢Пo`W(xu)g(sh)µ¼l(f)
4Іλ֧r(sh)(yn)cІλP(gun)ϵcԺϵ
P(gun)ϵ(sh)(yn)Ƿؔ(ci)(d)ĿЌ(sh)wІλǷo茍(sh)(yn)Ҫ(d)ĽеČ(sh)(yn)ҿgֵºؔ(ci)(w)(qun)ش(xing)(jng)M(fi)ֵ֧ȷrĿǰچ}һİl(f)չ˼·c(din)(sh)(yn)Ұl(f)չh
ʾP(gun)ڡ201*Ⱥڌ(sh)(yn)վйY(ji)oķHչ˼Sʹ201*Ⱥڌ(sh)(yn)վйY(ji)ԓƪ½h(chung)
ԴW(wng)j(lu) ؟(z)ăHތW(xu)(x)a(chn)(qun)}Ո(lin)ϵ҂r(sh)h